Locked and Loaded

Locked & Loaded: An Aggressive Smart Lock

Trans-acting glmS catalytic riboswitch: locked and loaded.

A recently discovered class of gene regulatory RNAs, coined riboswitches, are commonly found in noncoding segments of bacterial and some eukaryotic mRNAs. Gene up- or down-regulation is triggered by binding of a small organic metabolite, which typically induces an RNA conformational change. Unique among these noncoding RNAs is the glmS catalytic riboswitch, or ribozyme, found in the 5'-untransl...

Dual-wavelength actively mode-locked laser-diode array with an external grating-loaded cavity.

We report the generation of dual-wavelength picosecond pulses by use of a commercial laser-diode array. The laser cavity incorporated a folded dispersive delay line with a V-shaped double-stripe mirror. The spectral separation of the laser output at the two wavelengths can be tuned from 2 to 11 nm. The actively mode-locked pulse widths at the two wavelengths were both 29 ps. Cross-correlation a...

High Speed Delay-Locked Loop for Multiple Clock Phase Generation

In this paper, a high speed delay-locked loop (DLL) architecture ispresented which can be employed in high frequency applications. In order to design the new architecture, a new mixed structure is presented for phase detector (PD) and charge pump (CP) which canbe triggered by double edges of the input signals. In addition, the blind zone is removed due to the elimination of reset signal. Theref...

Locked Plating: Biomechanics and Biology

Since the early ideas of internal fixation, many different concepts and techniques have been developed for the use in fracture surgery. Each technique has been welcomed by many with excitement while others have suggested caution, locked plating is no exception. Since its advent over 15 years ago many have viewed this as a violation of the strict AO principles of anatomic reduction and rigid fix...